Introduction, Ian H. Gotlib & Constance L. HammenI. Descriptive Aspects of Depression1. Epidemiology of Depression, Ronald C. Kessler, Peter de Jonge, Victoria Shahly, Hanna M. van Loo, Philip S.-E. Wang, & Marsha A. Wilcox2. Assessment of Depression, Arthur M. Nezu, Christine Maguth Nezu, Minsun Lee, & Jessica B. Stern3. Methodological Issues in the Study of Depression, Rick G. Ingram, Greg J. Siegle, & Dana Steidtmann4. Course of Depression: Persistence and Recurrence, Daniel N. Klein & Anna E. S. Allmann5. Comorbidity of Unipolar Depressive and Anxiety Disorders, Susan Mineka & Suzanne Vrshek-Schallhorn6. Emotional Functioning in Depression, Jonathan Rottenberg & Lauren M. Bylsma7. Depression and Medical Illness, Kenneth E. Freedland & Robert M. Carney8. Features and Course of Bipolar Disorder, Eric Youngstrom & Guillermo Perez AlgortaII. Vulnerability, Risk, and Models of Depression9. Genetics of Mood Disorders, Jennifer Y.F. Lau, Kathryn J. Lester, Karen Hodgson, & Thalia C. Eley10. Neurobiological Aspects of Depression, Michael E. Thase, Chang-Gyu Hahn, & Olivier Berton11. Neuroimaging Approaches to the Study of Major Depressive Disorder: Regions to Circuits, Diego A. Pizzagalli & Michael T. Treadway12. Early Adverse Experiences and Depression, Sherryl H. Goodman & Cara M. Lusby13. Children of Parents with Depression, Ian H. Gotlib & Natalie L. Colich14. Cognitive Aspects of Depression, Jutta Joormann & Kimberly A. Arditte15. Depression and Interpersonal Processes, Constance L. Hammen & Josephine Shih16. The Social Environment and Depression: The Roles of Life Stress, Scott M. Monroe, George M. Slavich, & Katholoki Georgiades17. Risk Factors for Bipolar Disorder, Sheri L. Johnson, Amy K. Cuellar, & Andrew D. PeckhamIII. Depression in Specific Populations18. Understanding Depression across Cultural Contexts, Yulia E. Chentsova-Dutton, & Andrew G. Ryder, Jeanne L. Tsai19. Gender Differences in Depression, Lori M. Hilt & Susan Nolen-Hoeksema20. Depression in Children, Brandon E. Gibb21. Depression in Adolescents, Karen D. Rudolph & Megan Flynn22. Depression in Couples and Families, Joanne Davila, Catherine B. Stroud, & Lisa R. Starr23. Depression in Later Life: Epidemiology, Assessment, Impact, and Treatment , Dan G. Blazer & Celia F. Hybels24. Depression and Suicide, Matthew K. Nock, Alexander J. Millner, Charlene A. Deming, & Catherine R. GlennIV. Prevention and Treatment of Depression25. Major Depression Can Be Prevented: Implications for Research and Practice, Ricardo F. Muñoz, Stephen M. Schueller, Alinne Z. Barrera, Huynh-Nhu Le, & Leandro D. Torres26. Pharmacotherapy and Other Somatic Treatments for Depression, Michael J. Gitlin27. Cognitive and Behavioral Treatment of Depression, Steven D. Hollon & Sona Dimidjian28. Pharmacotherapy and Psychosocial Treatments for Bipolar Disorder, David J. Miklowitz29. Couple, Parenting, and Interpersonal Therapies for Depression in Adults: Toward Common Clinical Guidelines within a Stress-Generation Framework, Steven R. H. Beach, Mark A. Whisman, & Guy Bodenmann30. Biological and Psychosocial Interventions for Depression in Children and Adolescents, Nadine J. Kaslow, Marissa N. Petersen-Coleman, & Ashley Maehr AlexanderClosing Comments and Future Directions, Constance Hammen & Ian H. Gotlib