Introduction to Genomics by Arthur M. Lesk (English) Paperback Book

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The most up-to-date and complete textbook for first time genomics students, Introduction to Genomics offers a fascinating insight into how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing.

FORMATPaperback LANGUAGEEnglish CONDITIONBrand New Publisher Description

Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine theirfunction? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook forstudents approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. TheOnline Resource Centre accompanying Introduction to Genomics features: For students: - Extensive and imaginative weblems (web-based problems) for each chapter designed to give youpractice with the tools required for further study and research in the field- Hints and answers to end-of-chapter problems and exercises support your self-directed learning- Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research - Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primaryliterature- Rotating figures allow you to visualize complex structuresFor registered adopters: - Downloadable figures from the book.

Author Biography

Arthur M. Lesk is Professor of Biochemistry and Molecular Biology at The Pennsylvania State University, USA.

Table of Contents

1: Introduction2: The Human Genome Project3: Mapping, Sequencing, Annotation, and Databases4: Evolution and Genomic Change5: Genomes of Prokaryotes and Viruses6: Genomes of Eukaryotes7: Comparative Genomics8: The Impact of Genomics on Human Health and Disease9: Genomics and Anthropology10: Transcriptomics11: Proteomics12: Metabolomics13: Systems Biology

Review

`Review from previous edition This book is great for introducing the field of genomics, providing the basic concepts underpinning the field, including cutting edge techniques, along with examples of its application.'Dr Emma Laing, University of Surrey`The writing is eloquent and engages the curious reader with a wide range of background stories. The practical applications are always highlighted. Rather than a text book studied to pass an exam, this book is a pleasure to read.'Dr Richard Bingham, University of Huddersfield`It's the best textbook that I have reviewed for upper level undergraduates. It has good basic coverage of human aspects, databases, and comparative genomics. I like the questions and problems at the end of the chapters.'Professor Michael Shiaris, University of Massachusetts Boston

Promotional

The most current, complete, and compellingly written textbook for those studying Genomics for the first time

Long Description

Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine theirfunction? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook forstudents approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. TheOnline Resource Centre accompanying Introduction to Genomics features: For students: - Extensive and imaginative weblems (web-based problems) for each chapter designed to give youpractice with the tools required for further study and research in the field- Hints and answers to end-of-chapter problems and exercises support your self-directed learning- Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research - Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primaryliterature- Rotating figures allow you to visualize complex structuresFor registered adopters: - Downloadable figures from the book.

Review Text

`Review from previous edition This book is great for introducing the field of genomics, providing the basic concepts underpinning the field, including cutting edge techniques, along with examples of its application. 'Dr Emma Laing, University of Surrey`The writing is eloquent and engages the curious reader with a wide range of background stories. The practical applications are always highlighted. Rather than a text book studied to pass an exam, this book is a pleasure to read.'Dr Richard Bingham, University of Huddersfield`It's the best textbook that I have reviewed for upper level undergraduates. It has good basic coverage of human aspects, databases, and comparative genomics. I like the questions and problems at the end of the chapters.'Professor Michael Shiaris, University of Massachusetts Boston

Review Quote

Review from previous edition This book is great for introducing the field of genomics, providing the basic concepts underpinning the field, including cutting edge techniques, along with examples of its application.

Feature

This fully updated and restructured new edition, which includes two new chapters, takes account of new developments and technologies, presenting a logical and coherent overview of genome science today.The author's widely-praised writing style leads the reader through a conceptually challenging subject in a clear, lucid way, building confidence in, and enthusiasm for, the subject at the outset.Broad and fascinating range of 'real world' examples, which are also relevant across genetics modules more widely.New 'looking forward' feature making the links between each chapter explicit and helping students connect seemingly different topics.Extensive learning tools throughout - most notably the exercises, problems and online weblems accompanying each chapter - encourage and support self-directed learning, helping the student to master the subject.An Online Resource Centre featuring an extensive range of resources for both lecturers and students, enhancing the value of the book as a teaching and learning tool.

New Feature

1: Introduction 2: The Human Genome Project 3: Mapping, Sequencing, Annotation, and Databases 4: Evolution and Genomic Change 5: Genomes of Prokaryotes and Viruses 6: Genomes of Eukaryotes 7: Comparative Genomics 8: The Impact of Genomics on Human Health and Disease 9: Genomics and Anthropology 10: Transcriptomics 11: Proteomics 12: Metabolomics 13: Systems Biology 1. Introduction 2. The Human Genome Project 3. Mapping, Sequencing, Annotation, and Databases 4. Evolution and Genomic Change 5. Genomes of Prokaryotes and Viruses 6. Genomes of Eukaryotes 7. Comparative Genomics 8. The Impact of Genomics on Human Health and Disease 9. Genomics and Anthropology 10. Transcriptomics 11. Proteomics 12. Metabolomics 13. Systems Biology

Details ISBN0198754833 Language English Year 2017 ISBN-10 0198754833 ISBN-13 9780198754831 Format Paperback Author Arthur M. Lesk Publisher Oxford University Press Edition 3rd Imprint Oxford University Press Place of Publication Oxford Country of Publication United Kingdom Media Book DEWEY 572.86 Pages 544 Position Professor of Biochemistry and Molecular Biology Publication Date 2017-03-30 Affiliation Professor of Biochemistry and Molecular Biology, The Pennsylvania State University UK Release Date 2017-03-30 NZ Release Date 2017-03-30 Illustrations 330 colour line, 49 colour half-tone Edition Description 3rd Revised edition Audience Undergraduate AU Release Date 2017-03-29 We've got this

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