Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second

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EAN	9781138297555
UPC	9781138297555
ISBN	9781138297555
Book Title	Handbook of Preformulation: Chemical, Biological,
Item Length	23.4 cm

Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development.

Entirely focused on preformulation principles, this fully revised and updated Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second Edition provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.

Features:

Addresses the preformulation studies of three different types of new active entities - chemical, biological, and botanical, which is the latest established class of active ingredient classified by the FDAIllustrates the activities comprised in preformulation studies and establishes a method of tasking for drug development projectsIncludes extensive flow charts for characterization decision makingGives extensive theoretical treatment of principles important for testing dissolution, solubility, stability, and solid state characterizationIncludes over 50% new material

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